Cryptococcus neoformans usually occurs as a primary pulmonary infection that can potentially disseminate in an immunocompromised host
to body regions such as the central nervous system, meninges, bone, or SC tissue.
1-4) Usually preceded by a disruption of the skin barrier of immunocompromised hosts
, cutaneous mucormycosis generally affects the extremities; it rarely occurs in the head and neck.
The acute fulminant form is seen in immunocompromised hosts
, and it is characterized by infection with Mucor or Aspergillus strains.
Although the lungs are the most common site ofinfection in the immunocompromised host
, the paranasal sinuses and the brain are the next most common.
In the immunocompromised host
, an uncontrolled proliferation of primarily colonizing or contaminating pathogens or commensals can progress to severe disease.
Head and neck lesions in the immunocompromised host
Mucormycosis supraglottis on induction of anesthesia in an immunocompromised host
Additionally, while Cryptosporidium infections are usually self-limited, some individuals, including the immunocompromised host
and especially those with advanced HIV and those who are solid organ transplant recipients, may have a protracted course of profuse diarrhea if infected.
First case report of Nocardia veterana causing nodular lymphangitis in an immunocompromised host
Chapters on emerging infections in the immunocompromised host
and on bioterrorism are also included.
The recognition that Candida is an important pathogen, particularly in the immunocompromised host
, has resulted in a vast body of in vitro investigations evaluating its virulent attributes in an attempt to elucidate the pathogenesis of the disease.
Volume 1 covers host-parasite relationships and the pathogenesis of infectious diseases, then presents infections of specific organ systems as well as systemic infections, infections of the fetus and newborn, and infections of the immunocompromised host