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In those with impaired glucose tolerance, that risk increased by roughly 5%, and in patients with IGT and impaired fasting glucose, the risk rose to more than 6%.
Among the 13 women with impaired glucose tolerance, glucose and insulin levels did not differ depending on the level of apnea risk.
To facilitate this effort, plasma from well-characterized individuals of diverse racial and ethnic backgrounds with normal glucose tolerance, impaired glucose tolerance, and type 2 diabetes will be made available to investigators for validation of potential new diagnostic tests.
Gestational impaired glucose tolerance was not a significant independent predictor of having a large-for-gestational-age infant," wrote Dr.
Mortality among the women and men with newly identified impaired glucose tolerance ran 0.
The investigators identified five study groups: those with gestational diabetes mellitus (GDM), 1-hour gestational impaired glucose tolerance (GIGT), 2 or 3 hour GIGT, abnormal glucose challenge test (GCT) with normal glucose tolerance (NGT), and normal GCT with NGT (Diabetes Care 2008; 31:1275-81).
Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance.
The researchers' analysis centered on 3,187 patients with impaired glucose tolerance and elevated fasting blood glucose levels who completed the Beck Depression Inventory and reported antidepressant use.
None of them was previously known to have either diabetes mellitus or impaired glucose tolerance or was taking hypoglycemic agents.
When they gave subjects the glucose tolerance test, a standard measure of how well the body processes sugar, they found 326 women had impaired glucose tolerance -- flawed glucose metabolism that leads to Type II diabetes in some cases.
Carrying out their study on lab mice, Tso's team found that mice deficient in apoA-IV had impaired glucose tolerance and insulin was not secreted to move glucose from the blood stream.