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Furthermore, in that early series, all patients with low intracranial pressure (<20 mm Hg) survived, and nearly all those with increased intracranial pressure died.
Understanding the pathophysiology and clinical implications of the Cushing reflex and other physical signs of increased intracranial pressure [Electronic version].
However, venous sinus narrowing/thrombosis could cause increased intracranial pressure as well.
If the air within the intracranial cavity becomes trapped by a "ball-valve" or "inverted pop bottle" mechanism, increased intracranial pressure may cause mass effect and neurologic deterioration.
More direct pathophysiologic explanations have included tissue-related events such as hypoxia or increased intracranial pressure.
Patients with secondary headaches can present with increased intracranial pressure, mass lesion, infection, hemorrhage, and inflammation.
2] Symptoms depend on the intracranial site and may include headache, seizures, cranial nerve deficits, hemiparesis, increased intracranial pressure, and dysphasia.
In the presence of increased intracranial pressure, the possible respiratory depressant effects and its potential to elevate cerebrospinal fluid pressure may be markedly exaggerated.
Decisions regarding treatment should be guided by associated factors including the presence of hematoma, increased intracranial pressure, or the involvement of eloquent brain tissue (close to areas of primary motor, sensory, or speech cortex) distal to the lesion (Chun et al.
The systemic hypertension acts on the carotid baroreceptors and the heart rate reflexly slows, resulting in bradycardia with high blood pressure, which may be acute, subacute, as in this patient, or even chronic depending on the timing of the onset and relief of the increased intracranial pressure (3-5).
Of those who do survive, an additional 30% to 50% will suffer a secondary injury from one or more of the following: rebleed, cerebral edema, increased intracranial pressure, or cerebral vasospasm (the most common complication of aSAH).

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