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Kolupaeva, "The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection," Genes and Development, vol.
Editing of kinetoplastid mitochondrial mRNAs by uridine addition and deletion generates conserved amino acid sequences and AUG initiation codons. Cell 1998; 6 (53): 401-411.
As expected, most eubacteria have a distinct indication of a Shine-Dalgamo region located just upstream from the initiation codon. There is also a general enrichment of A's near the start with the exception of a clear decrease at position -1.
In this study, 25mer ASOs targeted to both the 5' terminal region and the AUG translation initiation codon region were highly inhibitory to in vitro translation.
Functional importance of RNA interactions in selection of translation initiation codons. Mol.
Similar to BA66019 strain, a second in-frame initiation codon is also seen at position 93-95.
Most of the protein-coding genes start with an ATG initiation codon, except for ND4, which starts with ATA.