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This caused a change in food innocuity from a posteriori approach to a reactive and punitive one in order to prevent and reduce the long term risk of the food chain.
In a dramatic letter to former Chancellor Hutchins, Rosenthal confirmed Kimpton's estimation of the forthcoming issue: "I do not at this point see how I can publish an issue with the criterion of innocuity. As we've got it planned, it won't be innocuous." But his letter also indicated his willingness to compromise: "I am willing to suppress it as an issue of the Chicago Review, if it means the magazine will not be killed."
A recombinant vaccinia-rabies virus in the immuno-compromised host: oral innocuity, progressive parenteral infection, and therapeutics.
The Hazard Analysis and Critical Control Point system (HACCP), recommended by different international organizations as the Codex Alimentarius Commission, the World Trade Organization (WTO), the International Office of Epizootics (OIE) and the International Convention for Vegetables Protection (ICPV) amongst others, contributes to ensuring the innocuity of food along the agroalimentary chain and requires of Good Manufacturing Practices (GMP) for its implementation, GMP's which are legislated in most countries.
Therefore, it is necessary to look for and design alternative storage methods during transport and distribution that will assure that quality and innocuity of the product will be maintained until it is offered to the consumer.
Food innocuity is a fundamental aspect of public health and an essential element to manage of total quality, for which it is a subject of the highest priority for all countries and governments.
Altogether, these human infections indicate that attenuation for animals does not necessarily mean innocuity for humans and that biological safety measures must be followed in each case.
The adoptions of innocuity and quality standards are defining new institutional, organizational and technological trajectories in global level.