Insula

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INSULA, Latin. An island. In the Roman law the word is applied to a house not connected with other houses, but separated by a surrounding space of ground. Calvini Lex; Vicat, Vocab. ad voc.

References in periodicals archive ?
Vestibular and visual responses in human posterior insular cortex. J Neurophysiol 2014;112:2481-91.
The pain video induced greater activation in the right posterior insular cortex, a region implicated in viscerosensory processing, and in the superior temporal sulcus, a region implicated in the perception of nonverbal social cues.
In a series of experiments, Bermudez-Rattoni's group has found that a damaged or destroyed insular cortex renders rats incapable of forming taste aversions.
"The insular cortex is involved in the detection and regulation of body temperature, so there is a large negative correlation between the activity of this structure and the magnitude of the temperature change," they said.
The insular cortex is a site of taste and illness input in the brain.
The insular cortex, or simply insula, is basically a hidden cortical region folded and tucked away deep in the brain - an island within the cortex.
Upon viewing photographs of their former partners, several key areas of participants' brains were activated, including the ventral tegmental area, which controls motivation and reward and is known to be involved in feelings of romantic love; the nucleus accumbens and orbitofrontal/prefrontal cortex, which are associated with craving and addiction, specifically the dopaminergic reward system evident in cocaine addiction; and the insular cortex and the anterior cingulate, which are associated with physical pain and distress.
"The more pronounced activation of the insular cortex in the men might be related to the autonomic components, such as elevated heart rate or increased sweating, that accompany watching emotional material," he added.
Researchers have found that, in addition to a pathway involving the insular cortex of the brain-the target of most recent research on interoception-an additional pathway contributing to feeling the heartbeat exists.
The researchers looked at the insular cortex - a part of the brain triggered by both feelings and observations of disgust - to see how participants responded to images of disgusted faces.
This showed that the risky decisions were preceded by activity in a brain area called the nucleus accumbens, while the safe bets followed excitation in the anterior insular cortex. (ANI)
Compared to placebo, administration of NYX-2925 resulted in statistically significant reductions of Glx levels in these key pain-regulating brain regions, including the dorsal anterior cingulate cortex at rest and the posterior insular cortex following an evoked pain stimulus.