The number needed to treat with physical therapy instead of intra-articular
corticosteroids in order for one additional patient to achieve at least a 50% improvement in WOMAC score through 1 year of follow-up was four.
Godwin et al9 in asystematic review concluded that intra-articular
corticosteroid injection results in clinically and statistically significant reduction in pain of OA knee 1 week after injection.
In our study, intra-articular
PRP injections were performed via the posterior approach under sonography guidance to identify anatomic structures and to minimize potential complications (9).
In this study, significant relationships were determined between the intra-articular
knee pathologies and the BC volume.
Patients received three weekly intra-articular
injections of 2 mL of sodium hyaluronate (Hyalgan, Fidia Farmaceutici S.
injection of steroids are thought to be linked to the destruction of the knee, but there is no strong evidence which supports the progression of knee disease by steroid injections.7,12 Triamcinolone is chondro-protective and doesn't allow osteophyte formation to take place.7,12 Overall, steroids are safer and better compared to alternative strategies such as NSAIDs, because this disease is common in old age where NSAIDs are linked to many complications.2,7 Hence, this lack of toxicity is the main factor responsible for making intra-articular
corticosteroid injections one of the main treatment options for KOA.7
foreign bodies usually provoke remarkable inflammation.
Changes of cartilage and bone markers after intra-articular
glucocorticoid treatment with and without postinjection rest in patients with rheumatoid arthritis.
Mean serum TNF-[alpha] level of the group that received only 0.9% NaCl solution injection without induction of OA to determine the effects of the trauma caused by intra-articular
injection and were kept for 6 weeks as the rest of the treatment groups (Group IV) was 7418.8571 pg/ml (Table 1).
Since distal radius fracture is a debilitating injury that causes a significant burden to the individuals and society, it should be treated effectively and safely in the shortest time after the injury to obtain best outcome.19 Distal radius fractures can usually be treated by closed reduction and non-invasive fixation in most of the cases.20 However, for extra-articular or minimally displaced intra-articular
fractures that are not stable with closed reduction and external fixation, surgical fixation should be performed.
MNX rats received intra-articular
injection of either 1.5 x [10.sup.6] mesenchymal stem cells labelled with 10 [micro]g/ml SiMAG (MSC-MNP; n =11 rats), 1.5 x [10.sup.6] mesenchymal stem cells (MSC-VEH; n =12 rats), or serum-free media (SFM; n =12 rats).
Physical exam demonstrated significant pain and guarding with passive hip motion, particularly hip flexion past 90 degrees, and provocative maneuvers such as both flexion/adduction/internal rotation (FADIR) and flexion/abduction/external rotation (FABER), suggesting an intra-articular
source of her discomfort.