I reviewed Krebs cycle
data for an additional 315 patients seen since my 2004 Townsend report.
Fermentation produces less ATP than aerobic respiration because it does not use the Krebs cycle
and the ETC.
The low expression levels of elongation factor Tu in the livers of ketotic cows minimize protein synthesis, indicating that most glucogenic amino acids take part in the Krebs cycle
and gluconeogenesis, which has limited the capacity for protein synthesis so that the protein synthetic machinery is down-regulated.
The unique position of SDH on the matrix side of the inner mitochondrial membrane enables SDH to participate in both the Krebs cycle
and the electron transport chain.
Our working hypothesis is that tryptamine inhibits succinate dehydrogenase (SDH), a Krebs cycle
enzyme that converts succinate to fumerate ultimately increasing ATP levels.
Any scientist will tell you he was the great man who developed the Krebs Cycle
on which much of modern biological theory depends.
Dichloroacetate, which increases flux into the Krebs cycle
, as well as in termediates of the Krebs cycle
, such as acetate and citrate, also enhanced the levels of PPSS I mRNA.
One learns the language of medicine while dissecting layers of tissue, poring over the microscope, and memorizing the Krebs cycle