Release and modification of 3H, 14C-lipopolysaccharide by isolated rat Kupffer cells
," Gastroenterology, vol.
CD68 has been proposed as an indicator for Kupffer cells
 and is used to distinguish Kupffer cells
from monocyte-derived macrophages [23, 27].
Radionuclide scans best demonstrate Kupffer cell
Pahl et al., "Importance of Kupffer cells
for T-cell-dependent liver injury in mice," The American Journal of Pathology, vol.
In the perivenular areas, Kupffer cells
containing ceroid pigments indicative of prior cellular injury and cell turnover are noted.
Yilmaz, "Hepatitis associated with aplastic anemia: do CD8(+) Kupffer cells
have a role in the pathogenesis?" Digestive Diseases and Sciences, vol.
Caption: FIGURE 1: Liver biopsy demonstrating increased iron content in hepatocytes and Kupffer cells
Frossard, "Neutrophil depletion-but not prevention of Kupffer cell
activation-decreases the severity of cerulein-induced acute pancreatitis," World Journal of Gastroenterology, vol.
The specific effect after constant glycine treatment is due to downregulation of glycine gated chloride channels on Kupffer cells
but not on neutrophils and alveolar macrophages.
It has been shown that high-fat diet increases Kupffer cells
number and induces their proinflammatory status, and cytokine and chemokine production by activated Kupffer cells
is involved in the pathogenesis of liver damage .
Immunostaining of Kupffer cells
in the liver and foam cells in the liver and the hepatic lymph node for MAC 387 antibody proved that these cells are macrophages.
They identified Kupffer cells
as sources of IL-1[beta] .