Sinusoi-dal spaces were reduced and Kupffer cells
increased, but the difference was not statistically significant (p-value = 0.
Morphometric Observations: The details of Numerical density of Kupffer cells
on the area (Nak) are summarized in Table 1.
In mice, the MCP1 produced by Kupffer cells
has been reported to exert monocyte-specific chemotactic activity and to be involved in inflammation within the liver .
Furthermore, further lipopoly-saccharide-induced activation of the Kupffer cells
, may contribute to the late liver dysfunction and to the increased synthesis of the lysosomal enzymes such as GLU .
Plasmodium spp sporozoites pass to humans through infecting mosquito bites and they are taken up by liver Kupffer cells
, which play an important role in conditioning the immune response and can act as antigen presenting cells.
Hepatic ischemia-reperfusion activates Kupffer cells
and initiates severe oxidative stress with enhanced production of reactive oxygen species (ROS) and TNF-[alpha].
Sinusoids, Kupffer cells
, and the central vein were also clearly visible (Figure 6).
The cell corda were separated by narrow blood sinusoids lined by endothelial cells and kupffer cells
are macrophages whose main role--removing bacterial and foreign proteins from the blood--is essential to the liver's primary function of cleansing the blood of foreign materials and toxic substances.
For liver, we analysed the centrality of nucleus, number of hepatocytes with binucleation, congestion of central vein, leukocytes infiltration, number of kupffer cells
and swelling lumen by the blood cells and congestion of sinusoids (Vieira et al.
Some cells possessed pyknotic nuclei, and numerous Kupffer cells
Nomadic or sessile: can Kupffer cells
function as portals for malaria sporozoites to the liver?