Changes in testosterone levels in diabetic men may be related to alterations in the Leydig cell
function (ARIKAWE et al.
Oxygen-mediated damage of microsomal cytochrome P-450 enzymes in cultured leydig cells
Although the testes of mammals present standard structure for several species, there is great variation in relation to volumetric proportion of its various components, especially in relation to the seminiferous tubules, Leydig cells
and proportion and disposition of vessels and lymphatics spaces (RUSSELL et al.
The majority of the circulating testosterone is made by the Leydig cells
Sex cord-stromal tumors comprise a heterogenous group of neoplasms that include GCTs of the juvenile and adult types, thecomas, fibromas, and tumors of Sertoli and Leydig cells
in isolation or combination, among others.
In utero and lactational exposures to diethylhexyl-phthalate affect two populations of Leydig cells
in male Long-Evans rats," Biology of Reproduction 80(5): 882-888.
The process of spermatogenesis depends on somatic testicular Leydig cells
and Sertoli cells that control germ cell development (Sharpe et al.
In males, LH stimulates testosterone production from specialized cells called Leydig cells
Obesity and a high fat diet poisons the Leydig cells
, reducing testosterone levels,
It is established that membrane damage and the formation of Leydig cell
autoantibodies are due to excessive alcohol intake, which effects Leydig cell
function by reducing testosterone synthesis and its metabolite, acetaldehyde.
INSL3, a Leydig cell
hormone that drives development of the gubernaculum, may underlie phthalate-induced cryptorchidism (Johnson et al.
The differential diagnosis includes juvenile granulosa cell tumor (JGCT), yolk sac tumor, cystic teratoma, Sertoli cell tumor, and Leydig cell