Novel compound heterozygous variants in the LHCGR gene identified in a subject with Leydig cell
hypoplasia type 1.
Stimulation of LH receptors in Leydig cells
leads to the secretion of testosterone hormone.
Protein kinase G-mediated stimulation of basal Leydig cell
The immuno-localization of HSD3B1 in the testis was restricted into Leydig cell
(Figure 6C, Table 3).
Steroidogenic Leydig cells
and apoptotic cells were labeled in cultured explants of GW 10-12 human fetal testis with an immunostaining of CYP11A1 (left panel) and an anticleaved caspase-3 antibody (right panel), respectively.
They screened 11 transcription factors that could affect the ability of Leydig cells
to produce testosterone.
Lee et al., "Gene expression analysis of toxicological pathways in TM3 leydig cell
lines treated with Ethane dimethanesulfonate," Journal of Biochemical and Molecular Toxicology, vol.
The seminiferous tubules and Leydig cells
were quantified by a stereological method [12-14].
Chen, "Regulation of Leydig cell
steroidogenic function during aging," Biology of Reproduction, vol.
An important physiological function of the ovary is to synthesize estrogen, whereas the Leydig cells
in testis are to synthesize testosterone (T).
increase their numbers but decline in steroidogenic function in the adult rat after neonatal hypothyroidism.
Effect of cisplatin on testicular tissue and the Leydig cell