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Related to Lysophosphatidic acid: lysophosphatidylcholine
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Altered activity of lysophospholipase D, which produces bioactive lysophosphatidic acid and choline, in serum from women with pathological pregnancy.
Lpathomab is an internally discovered, first-in-class antibody targeting Lysophosphatidic Acid, or LPA, a bioactive lipid that has been characterized in the scientific literature as playing a key role in nerve injury and neuropathic pain.
Edg receptors are G-protein coupled receptors that bind either 1-oleoyl lysophosphatidic acid (LPA) or sphingosine 1-phosphate (S1P).
TM](an antibody targeting lysophosphatidic acid, or LPA), for which investigational new drug (IND) enabling studies have been completed.
Lpath's second product candidate, Lpathomab(TM), is a monoclonal antibody against lysophosphatidic acid (LPA), a key bioactive lipid that has been long recognized as a significant promoter of cancer-cell growth and metastasis in a broad range of tumor types.
Discovery and Anti-Fibrotic Activity of Novel Antagonists of Lysophosphatidic Acid Receptor 1 (LPAR1), Publication #A2018, Poster Board #C77 Poster session on Sunday, May 18, Session Time 8:15 a.
5-year grant to develop its antibody therapeutic, Lpathomab(TM), which is directed against the bioactive lipid lysophosphatidic acid (LPA) for the treatment of traumatic brain injury (TBI).