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Although it is widely believed that disseminated MAC disease results from reactivation of a latent infection, recent data suggest that the disease may develop from recent infection via the respiratory or gastrointestinal tract.
In this updated report, the most important changes are a) the elevation from a B to an A rating of prophylaxis against disseminated MAC disease for both adults and children who have low CD4+ T-lymphocycte counts (Tables 2A and 3A), b) the recommendation that clarithromycin or azithromycin be considered first-choice drugs for MAC prophylaxis, with rifabutin as an alternative, and c) the elevation from a B to an A rating of vaccination against S.
If you get MAC disease, you will be treated with special medicines.
Three patients with pulmonary MAC disease and 1 with M.