In this report, a case born to a mother with syphilis, and diagnosed via maculopapular rash
on the second day of life is described in order to emphasize the importance of early treatment in congenital syphilis.
double dagger]) Definition used in the United States (interim, February 2016; confirmed, June 2016) states that clinical criteria for noncongenital Zika virus disease are defined as >1 of the following acute onset of fever, maculopapular rash
, arthralgia, and conjunctivitis.
Infection by ZIKV, can be asymptomatic in a large proportion of infected people (around 80%), and usually causes a mild clinical picture characterized by short-term, low-grade fever, followed by maculopapular rash
in the first or second day and intense pruritus.
Further studies are needed to determine the exact mechanism for the emergence of maculopapular rash
due to agomelatine.
Patients and Methods: All patients with cutaneous drug eruptions seen at the Dermatology Department of Mayo Hospital, Lahore, over 6 months were enrolled and the pattern of drug eruptions like urticaria, angioedema, fixed drug eruption, maculopapular rash
, erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis etc.
Symptoms may be present up to 10 days before an erythematous, maculopapular rash
The salient clinical features of SF include the primary lesion, inoculation eschar (tache noire), headache, malaise, fever, generalized myalgia, a pink maculopapular rash
and hepatosplenomegaly as was seen in the patient.
In this case, the maculopapular rash
represents a hypersensitivity drug reaction with associated fever.
Three days later, maculopapular rash
was observed in the perineal area with desquamation.
On the day following the pathologic diagnosis of "histologic findings consistent with prodromal stage of measles," a typical erythematous maculopapular rash
began on the child's face and spread to his trunk and limbs.
Ten percent of all patients on lamotrigine will develop erythema and a maculopapular rash
, usually within the first 28 weeks of therapy.