Sign and symptom duration was 1-5 days, and most patients had a maculopapular rash
, myalgias, fever, and headache.
The skin manifestations of erythema nodosum, a maculopapular rash
, or erythema multiforme represent a reaction to the primary pulmonary infection.
Further studies are needed to determine the exact mechanism for the emergence of maculopapular rash
due to agomelatine.
The salient clinical features of SF include the primary lesion, inoculation eschar (tache noire), headache, malaise, fever, generalized myalgia, a pink maculopapular rash
and hepatosplenomegaly as was seen in the patient.
In this case, the maculopapular rash
represents a hypersensitivity drug reaction with associated fever.
The combination of TORISEL and sunitinib resulted in dose-limiting toxicity (Grade 3/4 erythematous maculopapular rash
, and gout/cellulitis requiring hospitalization).
Three days later, maculopapular rash
was observed in the perineal area with desquamation.
In 2000, a 47-year-old woman presented with a 4-week history of cervical lymphadenopathy in the posterior triangle and associated fever, lethargy, and a maculopapular rash
on her upper limbs.
One of the signs is the occurrence of a maculopapular rash
in up to half the patients presenting with symptoms.
Rarely, a maculopapular rash
may be present adjacent to the tache noire.
Phenytoin hypersensitivity syndrome is a rare (1-4 in 10,000 patients) and important entity characterized by maculopapular rash
, fever, lymphadenopathy, hypertransaminasemia, and peripheral eosinophilia.
Ten percent of all patients on lamotrigine will develop erythema and a maculopapular rash
, usually within the first 28 weeks of therapy.