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Most common cutaneous manifestation observed in this study was maculopapular rash (59.4%), as has been reported in other studies too.10-12 The rash appeared within 2-3 days of the onset of fever and subsided within first week in all the patients; earliest after 2 days and latest after 6 days of onset of fever, thus was abrupt in onset, short lasting and was associated with moderate to severe pruritus in most of the patients in this study (78.9%).
The bilateral lower extremities demonstrated a maculopapular rash (Figure 1).
Among the various known patterns of CADRs, the most common was maculopapular rash (26%), followed by fixed drug eruptions (FDEs) (21.7%), and erythematous rash (21.3%) (Figure 1).
Adult-onset Still's disease (AOSD) is a rare systemic inflammatory condition with unknown etiology that is characterized by high spiking fever, arthritis, typically salmonpink maculopapular rash, leukocytosis with neutrophilia, and multiple organs' involvement [1].
Upon arrival, the patient was noted to have swelling of the RUE with diffuse large blisters (Figures 1-3) in addition to a generalized maculopapular rash (Figure 4).
The maculopapular rash was nonerythematosus, nonblanching, and not tender to touch.
Both developed prodromal symptoms the day after their return, then a generalized red maculopapular rash 2 days later.
Characteristic clinical findings are acute onset of fever with maculopapular rash, arthralgia, or conjunctivitis.
The illness was characterized by maculopapular rash, fever, myalgias/arthralgia, conjunctivitis, severe rash in arms and legs, and low grade fever.
Fever is usually higher than 100.9 F followed by diarrhea, vomiting and maculopapular rash whilesymptoms of kidney and liver function also appeared.
Symptoms of Zika virus infection include initial fever, a maculopapular rash, arthralgia, and sometimes conjunctivitis.