dose

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The firm aims to start and submit to Polish regulatory authorities for approval, a protocol amendment that is to continue dose escalation for the Phase I component of the study beyond Cohort 8 in the event the maximum tolerated dose is not reached in Cohort 8.
Conducted by Kosan and Roche as part of a global partnership to jointly develop and commercialize KOS-862, the Phase I trials were designed to determine the maximum tolerated dose, toxicity profile, pharmacokinetics and pharmacodynamics of intravenous KOS-862.

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