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Indeed, the mechanism of action for ETOP was predicted with 100% accuracy.
Galeterone is a proprietary small molecule, oral drug for the treatment of prostate cancer that disrupts androgen receptor signaling via a novel triple mechanism of action.
To improve our understanding of the basic biology of brain development, as well as the site and mechanism of action of environmental chemicals that target the thyroid system, we must increase the use of "-omics" technology (e.
This lack of elimination of bactericidal action suggests that these agents possess a secondary bactericidal mechanism of action that does not depend on the synthesis of protein and RNA, and that may be active when the bacteria are in a nonreplicating state (46).
president and chief executive officer of Gentium, said, "We are very pleased to have Professor Holler lecture on Defibrotide as further knowledge of its mechanism of action leads to a better understanding of its clinical potential in a number of important medical indications of unmet need.
The discovery of XD4241 and the subsequent identification of its mechanism of action validates our systems biology approach to drug discovery and demonstrates how it can rapidly and efficiently identify new drug leads.
The NIEHS Division of Extramural Research and Training (DERT), in collaboration with the National Toxicology Program (NTP), initiated a unique grants program in 1997 that funds investigator-initiated research to provide data to aid in defining the mechanism of action of agents under study by the NTP.
NASDAQ:GENT) today announced that mechanism of action data on Defibrotide will be presented in a poster entitled "Defibrotide, A DNA-Based Drug, Modulates Immune Functions Of The Endothelium: Impact For Cancer Therapy And Transplantation," authored by G.
This report provides comprehensive information on the therapeutic development for Myocardial Fibrosis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
The primary mechanism of action for decitabine is thought to be the correction of DNA hypermethylation, a major mechanism for regulating gene expression.