Laude et al., "High levels of antibodies against Merkel cell
polyomavirus identify a subset of patients with Merkel cell
carcinoma with better clinical outcome," Journal of Clinical Oncology, vol.
Effect of radiation therapy on survival in patients with resected Merkel cell
carcinoma: a propensity score surveillance, epidemiology, and end results database analysis.
carcinoma metastatic to the head of the pancreas.
carcinoma during treatment with TNF-alpha inhibitors: coincidence or warning?.
A virus called Merkel cell
polyomavirus (MCV) is suspected to contribute to the development of the majority of MCC.
Ordinarily, contact with the skin surface activates Ruffini corpuscle endings and Merkel cell-neurite complexes, with the Merkel cells
producing long-lasting nerve impulses.
Epidemiology of primary Merkel cell
carcinoma in the United States [published correction appears in I Am Acad Dermatol.
Characterized as a rare and aggressive neuroendocrine cutaneous cancer, Merkel cell
carcinoma (MCC) most commonly occurs in the head and neck region of elderly and immunocompromised patients.
Bladder cancer and seroreactivity to BK, JC and Merkel cell
polyomaviruses: The Spanish bladder cancer study.
For Merkel cell
carcinoma, a rare type of skin cancer, current smokers had a worse survival rate than those who had never smoked, though the difference was not statistically significant.
Differential diagnosis in this case includes the possibility of the lung mass being a metastases from a primary neuroendocrine carcinoma of the skin (Merkel cell
carcinoma, primary small cell carcinoma of the skin)--an uncommon but aggressive skin tumor with a propensity to metastasize to the lung.
These include WU (WUPyV), KI (KIPyV), Merkel cell
(MCPyV), and Malawi (MWPyV) PyVs, all of which have been detected in respiratory secretions, particularly from children (3).