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Related to Muscarinic receptors: cholinergic receptors
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The KarXT program has the potential to fulfill the long-held promise of therapeutics targeting muscarinic receptors.
Autoantibody activation of beta-adrenergic and muscarinic receptors contributes to an "autoimmune" orthostatic hypotension: Receptor autoantibodies in orthostatic hypotension.
There are five subtypes of muscarinic receptors expressed in the bladder.
The muscarinic receptor is a kind of GPCR, while [beta]-arrestin-1 is known as a terminator of GPCR signaling.
These results indicate that the activation of SERCA and muscarinic receptors may play an important role in the effect of DECC on the cardiac contractility, heart rate and coronary flow.
Molecular characterization of M2 and M3 muscarinic receptor expression in bladder from women with refractory idiopathic detrusor overactivity.
The stimulation of muscarinic receptors on the detrusor by acetylcholine, which is physiologically released from activated cholinergic nerves, is the main mechanism of bladder contraction (Chapple et al.
At the level of the endplate, acetylcholine binds to muscarinic receptors.
The scientists focused on muscarinic receptors, which regulate the speed of the heart, contraction of the pupil, and other bodily functions.
3] represent pharmacologic definitions, which are based on the actions of various drugs that bind muscarinic receptors selectively.
Food and Drug Administration has approved a muscarinic receptor antagonist for treating overactive bladder that is more selective to the muscarinic receptors in the bladder than some older drugs in this class.
Antagonism of cholinergic muscarinic receptors in the overactive bladder reduces urinary frequency and urgency.