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MUTATION, French law. This term is synonymous with change, and is particularly applied to designate the change which takes place in the property of a thing in its transmission from one person to another; permutation therefore happens when, the owner of the thing sells, exchanges or gives it. It is nearly synonymous with transfer. (q.v.) Merl. Repert. h.t.

A Law Dictionary, Adapted to the Constitution and Laws of the United States. By John Bouvier. Published 1856.
References in periodicals archive ?
The researchers suggested that the primary mutation sensitises an individual to a particular disorder and that the genetic background sets the trajectory for potential clinical features.
In exon 21, six mutation types were all point mutations, and mainly was L861Q.
Vertex Pharmaceuticals announced that Health Canada approved PrSYMDEKO for treating the underlying cause of cystic fibrosis in people ages 12 and older who have two copies of the F508del mutation in the cystic fibrosis transmembrane conductance regulator gene, or who have one copy of the F508del mutation and one mutation in the CFTR gene.
Most common mutation in rpoB was S531L in 75 (77%) isolates followed by D516V in 10 (10%) and H526Y in 6 (6%) samples respectively.
CF is caused by mutation in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR; #602421) gene which encodes a small ATP- and cAMP-dependent chloride channel placed on the apical border of epithelial cells of intestine, respiratory systems, pancreas, gall bladder, and sweat glands (1).
On the other hand, the spontaneous mutations in the germline of the putative father at any genetic marker locus used in the analysis can lead to an erroneous exclusion because such mutation results in differences between the parent and offspring.
FMF is known as an autosomal recessive hereditary disease with different clinical presentation due to type of mutation, i.e., homozygote or heterozygote pattern.
"In addition to scientists studying shared genetic mutations across large groups of individuals, here we're applying a set of smart, sophisticated tools that tell us what any specific mutation is going to do, even those that are rare or never observed before."
PCR for NPM1 mutation was performed using complimentary DNA by Amplification Refractory Mutation System Methodology.
(1) These include epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) (gefitinib, erlotinib, and afatinib) for EGFR mutations, combined dabrafenib (BRAF inhibitor) and trametinib (MEK inhibitor) for BRAF p.V600E mutation, and ALK tyrosine kinase inhibitors (crizotinib, ceritinib, and alectinib) for ALK translocations.
Using the mutation patterns in the hematopoietic stem and progenitor cells (HSPCs) the team was able to trace the developmental lineage tree of the cells.
Using the mutation patterns in the hematopoietic stem and progenitor cells (HSPCs) the team was able to trace the developmental lineage tree of the cells.shown that the number of mutations in healthy and leukemic blood stem cells does not differ.