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MUTATION, French law. This term is synonymous with change, and is particularly applied to designate the change which takes place in the property of a thing in its transmission from one person to another; permutation therefore happens when, the owner of the thing sells, exchanges or gives it. It is nearly synonymous with transfer. (q.v.) Merl. Repert. h.t.

A Law Dictionary, Adapted to the Constitution and Laws of the United States. By John Bouvier. Published 1856.
References in periodicals archive ?
Our study has been successfully extended to prenatal diagnosis and screening program in studied population and four mutations (R334W, [DELTA]F508, K710X and D110H) with total proportion of 77.7% were suggested for molecular analysis among studied populations.
Objective: To examine the frequency and distribution of mutations in the 'hot spot regions' of drug-resistant genes.
Summary: TEHRAN (FNA)- Leveraging artificial intelligence techniques, researchers have demonstrated that mutations in so-called 'junk' DNA can cause autism.
Nucleophosmin, nucleolar phosphoprotein B23, located within the nucleolus, is a nucleocytoplasmic shuttling protein involved in chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm as well as regulating the ARF-p53 tumor suppressor pathway.5 Mutations in the nucleophosmin (NPM1) gene are the most frequently occurring gene mutations in AML.6 These mutations identify patients that respond better to chemotherapy and have improved outcomes.7
(1) These include epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) (gefitinib, erlotinib, and afatinib) for EGFR mutations, combined dabrafenib (BRAF inhibitor) and trametinib (MEK inhibitor) for BRAF p.V600E mutation, and ALK tyrosine kinase inhibitors (crizotinib, ceritinib, and alectinib) for ALK translocations.
UTRECHT, The Netherlands, November 28, 2018 -- Researchers here have shown that the number of mutations in healthy and leukemic blood stem cells does not differ.
Using the mutation patterns in the hematopoietic stem and progenitor cells (HSPCs) the team was able to trace the developmental lineage tree of the cells.shown that the number of mutations in healthy and leukemic blood stem cells does not differ.
A new study led by researchers at Penn State revealed that the total amount of rare mutations -- deletions, duplications, or other changes to the DNA sequence -- in a person's genome can explain why individuals with a disease-associated mutation can have vastly different symptoms.
Previous studies have observed the efficacy of EGFR-TKIs in the most commonly targeted exon mutations (19 and 21).
Objectives: To investigate hotspot mutations in rpoB, katG and inhA genes and its possible co-relation with predominant genotypes in Khyber Pakhtunkhwa, Pakistan.
On the other hand, the spontaneous mutations in the germline of the putative father at any genetic marker locus used in the analysis can lead to an erroneous exclusion because such mutation results in differences between the parent and offspring.
To the best of our knowledge, there is no published study indicating mutations in the MEFV gene in asymptomatic parents of FMF patients, so we discovered MEFV gene of healthy and asymptomatic parents, who had an offspring suffering from FMF attacks and had at least one known mutation.