H and EX40-Sheets of Squamous Metaplastic Cells wth Few
Myoepithelial Cells, Scant Stroma
Flattened
myoepithelial cells with long cytoplasmic processes were observed between the epithelial cells and basement membrane of intercalated ducts, as reported in human beings by Yaku.
Caption: Figure 1: Hematoxylin and eosin, 40x,
myoepithelial cells arranged in a fascicular nested pattern separated by collagen stroma.
A, Myoepithelioma exhibits nests of
myoepithelial cells in a chondromyxoid stroma.
[7] Another theory is that the squamous changes in the breast probably begin within the
myoepithelial cell layer, before eventually involving the entire acinus.
(1,13,16,17,19,20) The best way to identify
myoepithelial cells is to use alpha-SMA or calponin, plus vimentin, because
myoepithelial cells in tumors are hardly ever fully differentiated, is Differences in the immunohistochemical profile are related to the myoepithelioma subtype and to a great deal of heterogeneity within each category.
However, the
myoepithelial cell layer may be attenuated or lost in benign and neoplastic apocrine proliferations.
Carcinomas of the breast showing
myoepithelial cell differentiation: a review of the literature.
An intervening
myoepithelial cell layer invariably resides in the papillary fronds.
Histogenesis of salivary gland pleomorphic adenoma (mixed tumor) with an evaluation of the role of the
myoepithelial cell. Hum Pathol 1982;13:62-75.
(47) Immunohistochemical stains can be employed in an attempt to highlight the presence of
myoepithelial cells around displaced glands; however, these stains are typically only helpful when a
myoepithelial cell layer is present, because staining may be attenuated or even absent in epithelial fragments that have undergone displacement (Figure 6, C).
Ossifying fibromyxoid tumor: modified
myoepithelial cell tumor: report of three cases with immunohistochemical and electron microscopic studies.