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Related to Nerve sheath tumor: neurofibromatosis
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5) Finally, druggable mutations that are known to be common in certain tumor types may also be common in others; for example, BRAF mutations, commonly associated with melanoma, have now been reported in malignant peripheral nerve sheath tumors and are associated with response to vemurafinib.
The lesion was highly suspicious for a peripheral nerve sheath tumor.
Malignant peripheral nerve sheath tumor (MPNST) and malignant triton tumor (MPNST with rhabdomyoblastic differentiation), potential candidates on morphologic grounds alone, arise often from a large peripheral nerve in patients with known neurofibromatosis.
CI = confidence interval; MPNST = malignant peripheral nerve sheath tumor.
Malignant peripheral nerve sheath tumors (MPNST) - Clinicopathological study and treatment outcome of twenty-four Cases.
These ultrastructural findings, though not specific, when taken in the context of the histology, histochemistry, and immunocytochemical evidence, were, however, supportive of an unusual form of spindle/epithelioid peripheral nerve sheath tumor.
They can also transform into deadly malignant peripheral nerve sheath tumors (MPNSTs), the leading cause of death in people with NF1.
Combined Marker Expression Patterns (MDM2 Amplification, p53 Immunohistochemistry, and MIB-1 Proliferation Index) for 15 Cases of Malignant Peripheral Nerve Sheath Tumor No.
Malignant peripheral nerve sheath tumor (MPNST) is a high-grade sarcoma that accounts for 10% of soft tissue tumors.
The malignant cases included 76 primary tumors, 7 metastases, 3 lymphoid malignancies (2 lymphomas and 1 plasmacytoma), 2 undifferentiated malignant tumors, and 1 malignant peripheral nerve sheath tumor (table).
Intraoperative biopsy was suggestive of a nerve sheath tumor.