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Related to Nerve terminal: synaptic cleft, Synaptic knob
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The neuromuscular junction is the place where the nerve and muscle are in close proximity and where the acetylcholine-containing vesicles are located in the nerve terminal.
In support of this possibility, it was recognized that the activities of many nerve terminal proteins were regulated by the ionization of specific cysteine sulfhydryl groups to highly reactive thiolates (Kiss 2000; Lipton et al.
4] receptors are known to facilitate ACh release at the myenteric neurons and nerve terminals of GI tracts, followed by producing the smooth muscle contractions (Chetty et al.
Suzuki et al (2) suggested that a gradual decrease in the amount of transmitter released from the presynaptic nerve terminals during TOF stimulation was the explanation for the delayed recovery of the TOF ratio, despite no delay in T1 recovery, although in their study, the duration of the operation and the supplemental doses of vecuronium and mepivacaine given were not detailed (2).
Chemical synapses involve the release of neurotransmittters by the presynaptic nerve terminal of one neuron, which then influences the function of a second neuron.
Most previous studies have relied on pudendal nerve terminal motor latency, but this test is abnormal only when the largest, most heavily myelinated nerves are damaged; it does not detect subtle injury.
The average pudendal nerve terminal motor latency (PNTML) score was 6.
However, these two nerves as a group, along with the more distal DF nerve terminal branches in the foot, could be distinguished from the nerve to the tibialis anterior in two of the specimens (2L, 2R).
Acetylcholinesterase is an enzyme in vertebrates that is responsible for breaking down acetylcholine into choline and acetic acid at the nerve terminal.
The tests--colonic motility study, anorectal manometry, defecography, electromyography and pudendal nerve terminal motor latency--serve to differentiate a pelvic outlet obstruction, which is the problem in a majority of patients, from colonic inertia.
After the MPTP attack, the dopamine-producing neurons still alive start to branch out, sending more fibers to the striatum, the area of the brain where the nerve terminal releases its precious cargo of dopamine.
Co-founder and Chairman of KineMed's Scientific Advisory Board and Chaired Professor at both UCSF Medical School and UC Berkeley, remarked that "It is exciting that two linked biochemical pathways -- the assembly-disassembly cycle of MTs in neurons and the MT-mediated transport of proteins along axons to the nerve terminal -- could be promising new therapeutic targets for neurodegenerative diseases.