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Related to Nuclear mutation: Nuclear DNA

MUTATION, French law. This term is synonymous with change, and is particularly applied to designate the change which takes place in the property of a thing in its transmission from one person to another; permutation therefore happens when, the owner of the thing sells, exchanges or gives it. It is nearly synonymous with transfer. (q.v.) Merl. Repert. h.t.

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In the presence of additional 12S rRNA gene mutations or nuclear mutations involved in transfer RNA modification (TRMU-MTO2 and GTPBP3 genes) or rRNA modification (TFB1M gene), the penetrance is higher (75).
Even larger pooled samples up to 100 000 individuals can be screened using optimized protocols already demonstrated for mitochondrial and nuclear mutations (27, 28).

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