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The neurons of nucleus accumbens were found to have significant ability to induce slow-wave sleep, which is characterized by high-voltage slow brain waves and accounts for the majority of our natural sleep.
In addition to the anterior limb of the internal capsule and the nucleus accumbens, all further surgery targets have been found to have good efficacy.
Widespread but regionally specific effects of experimenter- versus self-administered morphine on dendritic spines in the nucleus accumbens, hippocampus, and neocortex of adult rats.
sup][3],[4] Pharmacological evidence also indicates that systemic administration of morphine increases the extracellular levels of DA and 5-HT in the nucleus accumbens (NAc) and striatum of mice.
Previous studies suggested that neurochemical dysfunction in nucleus accumbens followed by systemic morphine administration was the main reason for dependency to morphine.
One projects to a reward center, the nucleus accumbens, and the other to a nearby fear center, the centromedial amygdala, the output station of the emotion hub.
In all of these disorders, a region called the nucleus accumbens, which provides a communication link between the emotional and reasoning centers of the brain, is particularly important because of its role in eliciting and modulating behavior.
The anatomical core of the reward system are dopaminergic neurons of the ventral tegmental area (VTA) that project to the nucleus accumbens, amygdala, prefrontal cortex and other forebrain structures (Koob & Volkow, 2010).
Studies on the brains of these motivation-sapped mice revealed a difference in a group of nerve cells in the nucleus accumbens, an area involved in the pursuit of rewards.
In addition, limonene reversed the increase in dopamine levels in the nucleus accumbens of rats given methamphetamine.