1) The proportion of control individuals with GSTM1 null mutation
was 33.3 % while in lung cancer cases it was 31.3 %.
An importance of the gene was confirmed in transgenic mice experiments--mice homozygous for a null mutation
in the PRLR gene were sterile due to a failure of embryonic implantation, demonstrated irregular cycles, reduced fertilization rates and defective embryonic development (Ormandy et al., 1997).
A null mutation
within the Pina sequence or point mutations and null mutations
within the Pinb sequence are associated with hard wheat kernel texture (Giroux and Morris, 1997, 1998).
elegans heterozygous for a collagen type IV null mutation
which causes embryonic lethality.
gene deletions), genotype A included patients with homozygous I2G or heterozygous I2G in trans with a null mutation
, and B patients with homozygous p.1173N mutation or heterozygous p.I173N mutation in trans with a mutation from group 'Null' or group A.
Atopic dermatitis; eczema; filaggrin; filaggrin null mutation
; ILC2s; interleukin-13; interleukin-25; nuocytes; toll-like receptors; type 2 innate lymphoid cells
A similar pattern of vascular calcification was observed in FH heterozygotes (due to a null mutation
of the LDLR), but was delayed by approximately 20 years in heterozygotes compared with homozygotes (6).
To evaluate the association between PCBs and GSTM1 null mutation
and their impact on the risk of endometriosis, the present study was undertaken to assertion whether women with endometriosis having higher concentrations of PCBs were more prone to carry GSTM1 null mutation
compared to those free from the disease.
Alturas has peak Rapid Visco-Analyzer flour viscosity similar to partial waxy genotypes Centennial and Penawawa and likely carries the null mutation
for Wx-B1 derived from its parent Centennial (Guttieri et al., 2001).
RNAi uses short dRNA oligo-nucleotides to regions of expressed portions of genes to phenocopy a null mutation
. Transgenic phenotypes expected will be similar to collagen type IV null animals.
The ttx-3 null mutation
causes the same behavioral defect as laser ablation of AIY, implying that AIY does not signal in this mutant (5).
of the prolactin receptor gene produces a defect in maternal behavior.