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The report provides a snapshot of the global therapeutic landscape for Atypical Chemokine Receptor 3 (Chemokine Orphan Receptor 1 or G-Protein Coupled Receptor 159 or G-Protein Coupled Receptor RDC1 Homolog or GPR159 or CXCR7)
Overexpression of orphan receptor tyrosine kinase Ror1 as a putative tumor associated antigen in Iranian patients with acute lymphoblastic leukemia.
Seeking the unknown binding partners for so-called orphan receptors, Yanagisawa and his team engineered cells to overproduce the cell surface proteins and then exposed the cells to extracts from brain tissue.
VTP-43742 is a phase II orally active retinoic acid receptor-related orphan receptor gamma t inhibitor indicated for psoriasis and other autoimmune disorders.
The a-ring lactone of brevetoxin PbTx-3 is required for sodium channel orphan receptor binding and activity.
M2 PHARMA-September 18, 2014-Indigo Biosciences unveils human estrogen-related orphan receptor gamma assay system
An orphan receptor is structurally related to a family of proteins that are known to act as functional cell-surface receptors but whose ligand has not yet been identified.