(redirected from Orphan receptor)
Also found in: Dictionary, Thesaurus, Medical, Encyclopedia, Wikipedia.
Related to Orphan receptor: orphan drug, Protein kinase A, Nuclear receptor, orphan nuclear receptor
See: receiver
Mentioned in ?
References in periodicals archive ?
Seeking the unknown binding partners for so-called orphan receptors, Yanagisawa and his team engineered cells to overproduce the cell surface proteins and then exposed the cells to extracts from brain tissue.
Emerging Role of Retinoid-Related Orphan Receptor (ROR) and Its Crosst alk With LXR(Liver X Receptor) in the Regulation Of Drug-Metabolizing Enzymes (Taira Wada and Wen Xie).
The collaboration builds on an original agreement between Merck and Lycera, announced in March 2011, that is focused on therapies targeting inhibitors of the retinoic acid related orphan receptor (ROR[eth][thorn]t), the key transcription factor coordinating both differentiation of T-helper 17 (Th17) cells and production of highly pro-inflammatory mediators such as interleukin-17 (IL-17).
These include statements related to the pending merger between X-Ceptor and Exelixis, the receipt, registration and value of shares, recording of a gain on those shares, and continued development of orphan receptor technology licensed by Ligand to X-Ceptor subject to future royalty payments.
a biopharmaceutical company developing breakthrough medicines to treat autoimmune diseases and cancer, today announced publication of research showing that sterols and sterol sulfates formed during cholesterol biosynthesis and processing are potent endogenous ligands for the retinoic acid receptor-related orphan receptor RORgamma.
APOMINE activates the Farnesoid X Receptor (FXR), an orphan receptor in the nucleus, and a cascade of biological signals within the cells that rapidly induce apoptosis without affecting normal, healthy cells," said Symphar Director of Research and Development Craig Bentzen, Ph.
1 Pipeline Programs Targeting Retinoic Acid Receptor-Related Orphan Receptor 49 5.
1 Pipeline Programs which Target RAR-Related Orphan Receptor (ROR) 61 5.