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Related to Paget's disease: Extramammary Paget's disease, Paget's disease of the bone
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Bill Local, from County Durham, has Paget's disease in his left shin bone.
He said: "A large number of people have Paget's disease but do not know about it.
Long-term control of bone turnover in Paget's disease with zoledronic acid and risedronate.
Key topics covered include strategic competitor assessment, market characterization, unmet needs and implications for the future market associated with Paget's disease.
The most potent bisphosphonates--risedronate (Actonel), alendronate (Fosamax), and pamidronate (Aredia)--are the most common treatments prescribed for Paget's disease.
Anorectal mucinous adenocarcinoma associated with latent perianal Paget's disease.
At baseline, serum cathepsin K levels were significantly higher in 60 Paget's disease patients, compared with 50 age-matched controls, and were higher in patients with polyostotic disease than in those with monostotic disease.
Clinicians also may get irritated by some of the statements such as, for instance, that the "Diagnosis of Paget's disease depends on the following findings: alkaline phosphatase level at least twice that of the upper normal range, characteristic radiography" (p 17).
Intravenous clodronate in the treatment and retreatment of Paget's disease of bone.
Q I would like more information about the medicine you suggested for the treatment of Paget's Disease.
Doctors treated each patient in eight 91-day cycles; during each cycle, the patient received either 1 g of phosphate or a placebo during the first three days, followed by 14 days of treatment with either a placebo or 400 mg of oral etidronate, a drug currently licensed only for the treatment of Paget's disease (bone inflammation).