pain

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Pain receptors are characterised by the ability to detect noxious stimuli, such as pinching and abrasion of the skin, while not reacting to light touch.
Pain receptors show up as early as seven weeks gestation* around the mouth, spread to the palms of the hands and soles of the feet by 11 weeks, the trunk, arms, and legs by the 15th week, and all remaining skin surfaces by the time the unborn child reaches the 20th gestational week (KJS Anand, et al, NEJM, 1987).
Nociception--the sensory process leading to the perception of pain--begins with stimulation of pain receptors in the tissues (see Figure 1, p22).
"The discomfort sensed by pain receptors in the area causes the message of pain to be sent via the bundle of nerves to the trigeminal nerve and on to the brain.
Prostaglandinss raise chemotactic activity, increase vascular permeability, sensitize pain receptors to inflammatory mediators and are a reason for pain after endodontic therapy.12 Pharmacological management of pain should be considered together with definitive dental treatment.13
How it works: Peppermint contains a natural anesthetic called menthol that dulls pain receptors. Peppermint oil can cause irritation if applied directly to the skin, so dilute it first.
Both types of receptors may be the main pain receptors for tissue damage and inflammation [26, 27].
"Another factor could be that pain receptors become more sensitive when surrounding temperature receptors that detect cold become more active."
"Another factor could be that pain receptors surrounding temperature receptors that detect cold become more active."
Because the retina doesn't have pain receptors, people won't feel a thing as their eyes get burned by the sun.
they feel better, and acupuncture improves blood flow, regulates over firing of the pain receptors, restores and strengthens the immune system without the severe side effects of pharmaceutical drugs."
The explanation of therapeutic effects of physical agents is based on the theory of control and modulation of painful impulses at: 1) peripheral level (mechanosensitive, thermosensitive and chemosensitive pain receptors); 2) spinal level (segmental--presynaptic system); 3) supra-spinal (central blocking system) [5, 6].