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Inherited platelet disorders (IPDs) are a heterogeneous group of conditions that can affect platelet number, platelet function, or both.
Key Words: Venous thrombosis, Blood platelet disorders, Platelet aggregation, Platelet function tests
21) It should also be considered that clinical features of functional platelet disorders in children are often missed or misdiagnosed.
FOCUS: HEMORRHAGIC PLATELET DISORDERS PLATELET FUNCTION TESTING: AGGREGOMETRY AND LUMIAGGREGOMETRY
Platelet dysfunction with a normal platelet count usually indicates a qualitative platelet disorder.
Investigation of platelet disorders should start with a measurement of the platelet count and review of peripheral smear morphology.
Platelet disorders can be classified according to disorders of platelet function.
Outside of von Willebrand in such patients, possible platelet disorders could include Glanzmann thrombasthenia (a platelet function disorder that is caused by an abnormality in the genes for glycoproteins IIb/IIIa) and platelet storage pool disorder, both of which should be diagnosed by a hematologist.
2 Platelet transfusion improves the management of patients with haemostatic or platelet disorders, reducing haemorrhagic complications and mortality.
Similarly, patients with active or history of malignancy, severe anemia, platelet disorders, bleeding and clotting disorders,pregnancy or breast feeding women,known patients of hepatitis B, C and HIV,alopecia totalis or alopecia universalis and those having tendency of poor wound healing and keloid were also excluded.
Bichile: Chapter 16 Platelet Disorders In: Munjal YP, Sharma SK, Agrawal AK, GuptaP, Kamath SA, Nadkar SA, Singal RK, Sundar S, Varma S, Pangte yGS, Prakash A, Shah SN editors API textbook of medicine 9th edition Jaypee Brothers 2012 table2 pp-987
Neurologists, neurosurgeons, cardiovascular, cerebrovascular, and other specialists from Europe, Asia, and North America discuss its epidemiology, emergency imaging, evidence-based critical care, blood pressure control, emergency reversal strategies for anticoagulation and platelet disorders, reperfusion-related intracerebral hemorrhage, cerebral microbleeds, nonvitamin K antagonist oral anticoagulants' reversal of intracerebral hemorrhage, ultra-early hemostatic therapy, ventriculostomy and lytic therapy, minimally invasive surgery, surgical strategies for acutely ruptured arteriovenous malformations, and prognosis and outcome.