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Related to Platelet factor 4: heparin, platelet factor 3


An event, circumstance, influence, or element that plays a part in bringing about a result.

A factor in a case contributes to its causation or outcome. In the area of Negligence law, the factors, or chain of causation, are important in determining whether liability ensues from a particular action done by the defendant.

West's Encyclopedia of American Law, edition 2. Copyright 2008 The Gale Group, Inc. All rights reserved.


n. 1) a salesman who sells in his/her own name on behalf of others, taking a commission for services. 2) something that contributes to the result.

Copyright © 1981-2005 by Gerald N. Hill and Kathleen T. Hill. All Right reserved.


1 a mercantile agent. An agent who is in the ordinary course of business entrusted with goods or documents of title representing goods with a view to their sale. A factor has a lien over goods entrusted to him; this lien covers any claims he may have against his principal arising out of the agency. Most factors will be mercantile agents (and have the powers of such) for the purposes of the Factors Act 1889. Under this Act, in certain circumstances a factor may pass a good title to goods entrusted to him.
2 an institution to whom a company assigns its book debts (see FACTORING).
3 in Scotland a landlord or superior's agent.
Collins Dictionary of Law © W.J. Stewart, 2006
References in periodicals archive ?
Table 1: Zeta Potential of and the cytotoxicity, hemolysis, C3 depletion and platelet factor 4 (PF4) on incubation with rasa chenduram and naga parpam Zeta potential Cell Viability Hemolysis (mV) (%) (%) Control -- -- -- Rasa chenduram -35.7 [+ or -] 1.06 40 [+ or -] 5 2.47 Naga parpam -32.6 [+ or -] 0.46 75 [+ or -] 5 0.34 C3 concentration PF4 concentration (mg%) (IU/ml) Control 127 7.5 [+ or -] 0.50 Rasa chenduram 125 18.4 [+ or -] 1 Naga parpam 126 7.5 [+ or -] 0.50 Table 2: Elemental analysis of rasa chenduram and naga parpam by EDAX Element Rasa chenduram Naga parpam Fe 11.10 4.68 Hg 88.91 0 Zn 0 95.32
Other negative/unremarkable studies included platelet factor 4 antibody, D-dimer, fibrinogen, serum immunoglobulins, Epstein-Barr virus polymerase chain reaction, and thyroid function tests.
In heparin-induced thrombocytopenia (HIT), unfractionated standard heparin binds platelet factor 4 (PF4), a heparin-neutralizing protein synthesized by megakaryocytes and stored in platelets.
In vitro platelet activation has consequences for the evaluation of heparin activity as well (4) because activated platelets might release platelet factor 4 (PF4), inactivating heparin and leading to artifactual shortening of activated partial thromboplastin time (APTT) results.
[Alpha] granules contain a number of different proteins, including fibrinogen, platelet-derived growth factor, von Willebrand factor, factor V, fibronectin, [Beta]-thromboglobulin, and heparin-neutralizing factor (platelet factor 4).[1,2] [Delta] Granules contain calcium, serotonin, pyrophosphate, adenosine diphosphate, and adenosine triphosphate.[1,2] Determination of storage pool organelles by transmission electron microscopy allows the identification of storage pool defects.
Immuno-globulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4. Blood.
1) The [alpha] granules contain platelet thrombospondin, fibrinogen, fibronectin, platelet factor 4, von Willebrand factor (VWF), [1] platelet-derived growth factor, [beta]-thromboglobulin, and coagulation factors V and VIII.
The use of citrate-theophylline-adenine-dipyridamol (CTAD) buffer rather than citrate decreased platelet activation as indicated by lowering the plasma concentrations of platelet factor 4 (12).
Platelet activation is measurable by quantifying thromboxanes, platelet factor 4, and thrombomodulin (TM).
Laboratory-based tests such as aggregometry, adhesion tests, viscometry, flow cytometry, electron microscopy, secretion assays, and measurements of platelet activation markers such as [beta]-thromboglobulin, platelet factor 4, or thromboxane [A.sub.2], can provide useful information.

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