Boxes denote the conserved binding sites of transcription factors in the XBP1
promoter region. Bolded sequences indicate the binding sequences of nuclear factor (NF-Y) (CCAAT), activating transcription factor 6 (ATF6), and XBP1 (CCACG).
Evolution of the proximal
promoter region of the mammalian growth hormone gene.
TRs in the
promoter region of cyp51A have previously been linked to increased cyp51A gene expression and MICs because of duplicated srbA transcription factor binding motifs (SRE1 and SRE2), leading to increased expression of cyp51A (14,15).
The purpose of this study was to identify a polymorphism in the
promoter region (-938C>A) of the BCL-2 gene.
This study has investigated five single nucleotide polymorphisms in TNF-[alpha] gene's
promoter region to evaluate their relationship with recurrent pregnancy loss disorder.
Effect of a Single Nucleotide Polymorphism in the LAMA 1
Promoter Region on Transcriptional Activity: Implication for Pathological Myopia.
Genetic polymorphisms within the coding and
promoter regions of proinflammatory cytokine genes have been described to regulate gene expression, ultimately altering cytokine production (9-11).
Among 106 INH resistant isolates, 97(91%) were associated with katG mutation while 24 (22%) with
promoter region of inhA.
A polymorphism (a nucleotide change from C to T) at position -889 of the
promoter region of the IL-1[alpha] gene has been reported, and this change suppresses the transcription of the IL-1[alpha] gene (18, 19).
(b) Chromatin immunoprecipitation for recruitment of Mediator ([alpha]-Med14), LexA-Med6ps ([alpha]-LexA), and TBP ([alpha]-TBP) to
promoter regions of chromosomal reporter ([8xlexA.sub.op]) and GAL1-10 (GAL1-10p) genes.
The methylation status of LC3A in the
promoter region and exon 4 including 6 and 8 CpG dinucleotides, respectively, was analyzed in cancer cell lines H226, COLO677, H322, and H1975 as well as in normal cells HBEC by BS (Figure 2).
Shin, "Evidence of the formation of G-quadruplex structures in the
promoter region of the human vascular endothelial growth factor gene," Nucleic Acids Research, vol.