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Related to Prothrombin complex concentrate: cryoprecipitate, Prothrombin time, Activated prothrombin complex concentrate
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Dabigatran-induced anticoagulant and bleeding effects can be reversed with both prothrombin complex concentrates and a specific antidote (idarucizumab) in a lethal porcine polytrauma model (O.
Treatment strategies to control active bleeding include the use of factor VIII concentrates, activated prothrombin complex concentrates (anti-inhibitor coagulant complex, Feiba, Autoplex T), and recombinant human factor VIIa (6), (8), (9).
FVII can be temporarily supplemented by infusing fresh frozen plasma, prothrombin complex concentrates containing factors X, IX, VII, and II derived from plasma, and recombinant FVIIa (NovoSeven[R]).
The report analyzes the markets for factor XIII concentrates, fibrinogen concentrates, albumins, antithrombins and prothrombin complex concentrates in the US, the top five countries in Europe (the UK, Germany, France, Italy and Spain), and Japan.

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