can occur after a neurological injury such as stroke.
PRISM: a novel research tool to assess the prevalence of pseudobulbar affect
symptoms across neurological conditions.
Veterans, OEF = Operation Enduring Freedom, OIF = Operation Iraqi Freedom, OND = Operation New Dawn, PBA = pseudobulbar affect
, PLC = pathological laughing and crying, PPV = positive predictive value, PTSD = posttraumatic stress disorder, ROC = receiver operating characteristic, SD = standard deviation, Se = sensitivity, Sp = specificity, SSN = Social Security number, TBI = traumatic brain injury, TRACTS = Translational Research Center for TBI and Stress Disorders, VA = Department of Veterans Affairs, VHA = Veterans Health Administration, VISN = Veterans Integrated Service Network.
the spectrum of clinical presentations, etiologies and treatments.
Less frequently, people with MS may have pseudobulbar affect
(PBA), a condition that can produce uncontrollable laughing or crying spells that are out of proportion to or disconnected from what people are feeling.
Biopharmaceutical company Avanir Pharmaceuticals Inc (NasdaqGS:AVNR) stated on Tuesday that NUEDEXTA (dextromethorphan hydrobromide/quinidine sulfate) has been granted approval in the European Union for the treatment of pseudobulbar affect
(PBA), irrespective of underlying neurologic disease or injury.
A Your father's behavior may well be symptomatic of a neurological condition called pseudobulbar affect
A combination of dextromethorphan hydrobromide and quinidine sulfate recently became the first treatment to be approved by the Food and Drug Administration for the treatment of pseudobulbar affect
, based on a study of patients with amyotrophic lateral sclerosis and multiple sclerosis.
Patients were given a test measuring how often they laughed or cried unintentionally due to a neural disorder known as pseudobulbar affect
Various terms have been previously used to describe this condition, including pseudobulbar affect
, affective and emotional lability, pathologic laughing and crying, emotional incontinence, and forced crying (Dark et al.
Nuedexta[R] is indicated for the treatment of pseudobulbar affect
ORLANDO -- The prevalence of pseudobulbar affect
symptoms--that is, uncontrollable, disruptive outbursts of crying and/or laughing--is considerably greater across a range of neurologic disorders than previously appreciated, according to the largest-ever study to screen for this condition.