Researchers at the University of Missouri have found neurological markers in the human brain that can be used to detect people at risk for developing psychotic disorders
and to understand when this risk has been successfully treated.
Those who reported using high-potency cannabis (delta 9-tetrahydrocannabinol greater than or equal to 10%)--also showed a significant 60% increase in the odds of psychotic disorder
, compared with never-users, which decreased slightly to 50% after controlling for daily use.
"Use of high-potency cannabis was a strong predictor of psychotic disorder
in Amsterdam, London, and Paris, where high-potency cannabis was widely available, by contrast with sites such as Palermo where this type was not yet available," the authors wrote.
They estimated that 43% of new cases of psychotic disorder
in Amsterdam were attributable to daily use of cannabis, and 50.3% were attributable to high-potency cannabis, compared with 1.2% and 2.3% of cases in Puy de Dome in France.
In our study, it was observed that the diagnoses of 43% of the individuals with first-line psychotic disorder
did not change during the follow-up period.
class="MsoNormalExperts may debate whether cannabis use can lead to psychotic disorders
, but they mostly agree on how to minimise one's risk.
For lifetime psychotic disorder
, the AUC was 0.80 for CMHS-M and 0.86 for CMHS-F.
All of these patients were identified with a psychotic syndrome and received the final DSM-IV-TR diagnosis of psychotic disorder
owing to a GMC.
Although in this case, the behavioral abnormality developed in close family members, it did not fulfill all the criteria of shared psychotic disorder
which led to the diagnostic dilemma.
Summary: Patients with severe psychotic disorders
face at least two challenges during pregnancy: the genetic risk of psychotic disorders
and the risk of teratogenicity caused by psychotropic drugs.
DSM - 5:- Diagnostic criteria for brief psychotic disorder
The case described close up of the category of acute and transient psychotic disorder
in ICD-10 or of the brief psychotic disorder
in DSM-5, based on duration criteria.