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RSV can also stay on hard surfaces for a long time, which is why parents should clean and disinfect surfaces whenever possible.
Also, this study will determine what, if any, boosting effect is seen from the additional shot when compared to the balance of subjects in the Phase 2 study, helping to determine whether MVA-BN RSV should be administered annually, or if the durability of the vaccine could extend across multiple seasons.
The elderly, also at high risk for RSV, would be another target population.
Therefore, while RSV currently remains the leading cause of hospitalisation for lower respiratory tract infection globally (~30-40% of all cases), it is hoped that the next 10 years will see the face of paediatric practice change once again, if some of the current passive and active RSV vaccine candidates are licensed.
Janssen is currently working on the discovery and development of multiple treatment and vaccine candidates against RSV infection, said Lawrence M.
Molecular detection of influenza virus and RSV: The specific nucleotide for the primer and probe in the gene coding from the complete genome of RSV and influenza viruses were obtained from gene bank.
Head-to-head comparison of the diagnostic accuracies of BD Veritor[TM] System RSV and Quidel[R] Sofia[R] RSV FIA systems for respiratory syncytial virus (RSV) diagnosis.
There is a high risk of serious RSV illness in infants who were born prematurely or who have bronchopulmonary dysplasia (BPD), congenital heart disease (CHD), congenital abnormalities of the airway or neuromuscular disease, or certain immunodeficiencies.
To investigate hMPV and RSV subtype A and B positivity using RT-PCR, a required study subsample size of 528 (Table 1) was calculated using standardized statistical methods, assuming the following parameters: estimated prevalence of hMPV infection in the RSV-negative population with ARI = 10% (14), estimated prevalence of RSV A or B subtype infection in the population with ARI = 7.
The initial chapters of this report provide an orientation of RSV partnering trends.
Molecular analysis of RSV-positive samples revealed that RSV A and B cocirculated during both seasons (98 A and 85 B during 2010-11; 99 A and 73 B during 2011-12).
We believe there will be great demand for a prophylactic vaccine that could help to reduce the burden RSV places on families and healthcare systems.