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With the help of the Maverix Analytic Platform, our first identified mutation associated with a progressive retinal atrophy in Persian cats provides a model for the study of blinding disease in humans.
The chocolate brown Labrador developed progressive retinal atrophy, a common genetic disease, when he was aged six and slowly lost his sight over a year.
1) Pars planitis (also called intermediate uveitis) is an inflammation of the uvea, part of the choroid lining in the eye which contains the blood vessels, that causes white blood cells and other inflammatory exudate to enter the vitreous humor (see Figure 1) and make white blobs (snowballs) build up, which impairs the vision and can lead to cataract, severe inflammatory glaucoma, swelling of the macula, retinal atrophy, and hemorrhage into the vitreous.