When GFAP was used as a marker for nonmyelinating Schwann cells
, (30) DCUN1D2 and NEDD8 signals were found in the GFAP-positive nonmyelinating Schwann cell
The regeneration of these injured peripheral nerves is associated with the demyelination, dedifferentiation, and proliferation of Schwann cells
, which takes place serially.
The scientists wrote in the journal Development: "The next step is to determine, for example in animal models of peripheral nerve injury, whether grafts of these Schwann cells
are conducive to nerve repair.
41) showed that heparin-binding forms of NRG1 (type I/II), secreted by the axons are required for early Schwann cell
survival and differentiation.
Demyelination and Schwann cell
responses adjacent to injury epicenter cavities following chronic human spinal cord injury.
Neurofibroma is a circumscribed but non-encapsulated tumor consisting of a mixture of schwann cells
, perineurial cells, and endoneurial fibroblasts.
We should point out that in one study, functional improvement was not observed following OEC transplantation but was observed following Schwann cell
The role of cultured Schwann cell
grafts in the repair of gaps within the peripheral nervous system of primates, Exp Neurol 1997:143:25-36.
Evaluated parameters were fascicle area and diameter, number and density of myelinated fibers and number and density of Schwann cell
The cells are of Schwann cell
origin, rounded, polygonal or spindled, and have a small/rounded nucleus.
The usual habitat in the nerve is the Schwann cell
but occasionally the ensheathed axon becomes involved.
Delayed myelination in mice without PMP22 suggests some function in Schwann cell
differentiation and the myelination process (Adlkofer et al.