"We are delighted about the successful collaboration in developing this 2'3'-cGAMP ELISA Kit as an important next generation tool to detect the second messenger
2'3'-cGAMP at an unprecedented sensitivity in the low pg/ml range," states Frank Schwede, Ph.D., the head of research and development at Biolog Life Science Institute.
(1984) The second messenger
linking receptor activation to internal Ca release in liver.
Our study demonstrated that WeFHG showed anti-hyperPRL activity via dopamine D2 receptor, which was related to the second messenger
cAMP and PKA.
PI(3,4,5)P3 is a lipid second messenger
involved in phosphate mediated activation of various downstream effectors associated with the oncogenic pathways .
In this later example the signal transduction pathway remains uncharacterized, but microvillar-type photoreceptive cells typically signal via calcium as a second messenger
(Koyanagi et al., 2008).
Genetic variations in drug action are due to alterations in the structure or activity of drug targets, second messenger
systems or downstream pathways.
binding of the bacterial second messenger
cyclic dimeric GMP interacts with a
Cyclic AMP (CAMP): Second messenger
molecule whose production by enzymes called adenylyl cyclases is regulated through receptor activation of G -proteins, and which itself activates certain protein kinases.
So-called metabotropic receptors , responding to the same neurotransmitters, set off chemical cascades in the receiving nerve cells, so-called "second messenger
" systems, chains of chemical processes activating synthesis of neurotransmitters, of receptors and of modulators, changing the reactivity of the nerve cell and of the system it subserves.
In the present study, we found that the second messenger
cyclic GMP may also be involved in the increase in midgut E-20-M activity (enzyme activity measured by radioassay).
In the second messenger
scene (III.3), Cleopatra's anxieties are dramatized in a slightly different (and paradoxical) way: because she has frightened the messenger, she is obliged to cross-question him rather than listening more passively to his report.
His text includes a discussion on the extracellular activity of neurons, and, briefly, on their intracellular functions, known as the second messenger