The second messenger
may then go on to activate a secondary effector, which may then produce another second messenger
, and so on.
In the past, many researchers centered their studies on the role played by inositols as second messengers
in insulin signaling transduction .
In this later example the signal transduction pathway remains uncharacterized, but microvillar-type photoreceptive cells typically signal via calcium as a second messenger
(Koyanagi et al.
Binding of the neurotransmitter to the receptor activates G -proteins, which in turn induce the production of second messengers
such as cyclic AMP (cAMP) that then activate kinases, ultimately resulting in the opening of ion channels in the cell's membrane.
This binding initiates a series of chemical reactions inside the cell, called the second messengers
, according to Fitzgerald.
The fourth treatment, theophylline, a phosphodiesterase inhibitor that prevents the breakdown of cyclic adenosine monophosphate (the second messenger
produced by adenylyl cyclase), was the only agent that restored cell signaling to normal or supranormal levels but did so at further cost to cell replication.
or 'Nanotechnology', the majority offer straightforward clear synopses of areas of basic physiology and pharmacology such as acid-base balance, temperature regulation, receptors and second messenger
We are particularly interested in the signaling cascade that utilizes the phospholipase C b4 (PLCb4) second messenger
Cyclic AMP has been implicated as a second messenger
in MIH action.
mediated second messenger
system causes saliva production in both the parotid and submandibular glands and enzymatic secretion in the parotid glands.
Earle Hyman is working on Tiresias, and Ruby Dee is the second messenger
An initial neurotransmitter will activate the fast ion channel receptor, while a second or third neurotransmitter will activate the second messenger
system that modifies the effect of the initial transmitter.