The head of each sperm cell is buried in the surrounding Sertoli cells
(red), which provide nourishment.
Neonatal exposure of BPA doses at 10 g/kg/day impairs fertility by protuberating Sertoli cell
junctional protein (adhesion, gap, and tight junction) that leads to impaired spermatogenesis (Salian et al.
Sex cord-stromal tumors, mainly Sertoli cell
tumor and Leydig cell tumor, can show solid growth patterns with diffuse clear cell change that resemble seminoma.
When SMAD3 is absent, Sertoli cells
take longer to respond to testosterone.
observed in some of the tubules were vacuolated preformed spermatids.
It is verified that the AAS did not significantly alter the numbers of the cell types evaluated; significant differences were not found either between the treated groups (STr and TTr) and the controls (SCo and TCo) as for the number of type-A spermatogonia and the number of Sertoli cells
During differentiation of germ cells in the testes, abnormal mitochondria were also reported in the spermatids and Sertoli cells
of the patient with encephalomyopathy.
Leydig cells produce testosterone, and Sertoli cells
nurture developing sperm cells.
But conjugated to FSH, small amounts of the drug go directly to the Sertoli cells
of the testes, the only cells in the male body with FSH receptors.
One possibility is that they need to be accompanied by sertoli cells
- special "nursing" cells found in the testes that have the job of nurturing growing sperm.
Topics include developing cell sources for transplantation, the use of bone marrow stem cells and Sertoli cells
, human neuroteratocarcinoma cells, the choroid plexus, immunoisolation for CNS cell therapy, evidence-based methodology, hematopoietic cell therapy, and stem cells and regenerative medicine.
14) Repeated episodes of inflammation could conceivably damage Sertoli cells