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Related to Sindbis virus: Sindbis fever
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In studying a strain of the Sindbis virus stripped of its capability to reproduce, however, the researchers noticed that the strain itself could invade and kill many types of cancer cells growing in lab dishes.
In our study participants identified by serology, both RT-PCR and culture were more sensitive than what others have found for Sindbis virus infection, for which 1 study found sensitivities of 7% and 1%, respectively (15).
However, the Sindbis virus failed to infect the salivary glands of A.
Brown, a molecular biologist at the University of Texas at Austin who has studied the Sindbis virus.
Sindbis virus is a model virus for the Alphavirus group, which contains the highly pathogenic and weaponizable Eastern, Western and Venezuelan equine encephalitis viruses.
In 1947, one of the largest WNV epidemics recorded occurred in the Karoo region of South Africa (5), and another occurred in combination with a Sindbis virus epidemic in 1983-84 in the Witwatersrand-Pretoria region of South Africa.
Towers and James Hudson grew Sindbis virus and mouse-cytomegalovirus in mouse cells, then exposed the cultures to the phototoxins in varying concentrations.
Testing for West Nile virus and Sindbis virus were done to rule out cross-reactions with endemic flaviviruses and alphaviruses, respectively.
These age-dependent disease and mortality rates have been previously observed with Sindbis virus (another alphavirus) and EEEV infection of laboratory mice (29,30).
Sindbis virus (SINV), a mosquito-borne virus that causes rash and arthritis, has been causing outbreaks in humans every seventh year in northern Europe.

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