His somatic stem cells
offer a way out of this dilemma: they are "only" multipotent, which means that they cannot give rise to all cell types but merely to a select subset of them - in this case, a type of cell found in neural tissue - a property, which affords them an edge in terms of their therapeutic potential.
Making full use of its in-house resources, Stelic is placing top priority on its strategy of patenting of somatic stem cell
therapeutic concepts and expanding the scope of associated patents with the objective of achieving market expansion.
Ghaemi, "A comparison between osteogenic differentiation of human unrestricted somatic stem cells
and mesenchymal stem cells from bone marrow and adipose tissue," Biotechnology Letters, vol.
The team did several experiments to be sure that the hub cells were involved, including one in which they genetically marked the hub cells and saw the mark appear in the newly formed somatic stem cells
- a clear sign that hub cells had divided to make new stem cells.
Studies which link fetal exposure to toxicants or other substances affecting somatic stem cells
that later populate organs such as the mammary gland, the prostate gland and the lung, and that have cancer as the endpoint, are sought by the NCI.
In adults, somatic stem cells
are a valuable source for tissue-specific cell types to replace aged or damaged cells .
During the study, researchers looked at fruit fly testes where two different stem cells exist: germline stem cells which give rise to sperm, and somatic stem cells
which develop into non-reproductive cell types.
This collection of nine papers describes aspects of stem cell research, including the application of stem cells and progenitor cells and vascular diseases, gas transcription factors and T cell development from hematopoietic stem cells, protein tyrosine phosphatase Shp-5 in cyyokine signaling and stem cell regulation, stem cells for neural tissue engineering, natural stem cell niche-dependency, potential applications of human umbilical cord stem cells in Whartons's jelly for the treatment of Parkinson's Disease, human oogenesis and follicular retrieval from ovarian somatic stem cells
and applications of gastric stem cells and the use of fibrocytes, mesenchymal stem cells and monocytes in research.
Recent work suggests that somatic stem cells
may have a much greater differentiation potential in different types of cells than previously thought (in experimental conditions, bone marrow stem cells are capable of differentiating into neurons, skeleton-muscular cells and cardiac muscle cells); therefore, the question arises whether research on embryonic stem cells is useful.
Studies that link fetal exposure to toxicants or other substances affecting somatic stem cells
that later populate organs such as the mammary gland, the prostate gland, and the lung, and that have cancer as the end point, are sought by the NCI.