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However, adverse effects were noted significantly more in the transfusion group and included urticarial, maculopapular rash, pruritus, chest pain, anaphylaxis, transfusion related acute lung injury and fluid overload.
The most common cause of transfusion-related mortality is Transfusion-Related Acute Lung Injury (TRALI), which has also been shown to be associated with transfusions from female donors.
Transfusion of blood and its products form one of the important pillars in the treatment of a patient in emergency department.
Lower rates of plasma transfusions meeting institutional guidelines were associated with institutions that used plasma with extended storage (1-5 days after thawing), and lower rates of plasma utilization tended to occur in larger institutions.
A patient receiving a blood transfusion should be provided with information regarding the purpose, anticipated benefits, expected outcome without transfusion, and any alternative measures.
Existing nursing literature includes information on adverse transfusion reactions, clinical presentation identifiable through nursing assessment, and recommended nursing actions in response to a reaction.
The association of red cell transfusions with post-operative infections has been shown in randomized clinical trials to be partially mitigated by leukoreduction.
In this study, 68,290 transfusions were given during 3-year study period (conducted in two tertiary-care centers) and with 3% overall incidence of transfusion reactions including TRALI which contributed only .
The History of Blood Transfusion in Sub-Saharan Africa, by William H.
Kyrgyzstan lacks blood transfusion stations, which would meet all requirements of the biosafety of blood and blood substitutes, as well as lacks proper examination of donors for HIV, hepatitis B and C," he noticed.
Whereas all transfusions have potential adverse reactions, the transfusion of massive amounts of stored blood is associated with unique consequences, such as shift to the left in the oxygen dissociation curve, acid base imbalance, hypothermia, hypocalcaemia, dilutional coagulopathy and respiratory distress.
Whole blood transfusions are rare in modern medicine - the main use is with autologous transfusion (when a patient has "pre-banked" blood for their own use).

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