ExPEC are characterized by pathogenic virulence factor
genes coding for various combinations of adhesins, toxins, iron-acquisition systems, capsule production, and toxins that enable them to cause disease once outside the host gut reservoir (32).
As each of these virulence factors
contributes to the pathogenicity of P.
'Characterization of Some Virulence Factors
Associated with Enterbacteriaceae Isolated From Urinary Tract Infections in Mansoura Hospitals', Egyptian Journal of Medical Microbiology, 2011; 20(2), 9-17.
The high virulence of serotype O157:H7 is attributed to Stx2 production, LEE and accessory virulence factors
carried on a plasmid, pO157 (21,38).
The study showed that Pseudomonas spp., Escherichia coli, Salmonella spp., and Staphylococcus aureus were the key pathogens implicated in neonatal infections in the center with most being resistant to conventional antibiotics and possessing virulence factors
. Staphylococcus aureus contributed most to the overall disease burden.
The Presence of Virulence Factors
Is Common in the Clinical Cohort.
Antagonistic effect of SNPs on Hla gene -as a major virulence factor
Association between the presence of enterococcal virulence factors
gelatinase, hemolysin, and enterococcal surface protein and mortality among patients with bacteremia due to Enterococcus faecalis.
Watsky et al suggests that although virulence factors
contribute to an organism's pathogenicity it is disruption of mucosal barriers which plays the major role in overcoming host defense.
Occurrence of virulence factors
and antibiotic resistances in Enterococcus faecalis and Enterococcus faecium collected from dairy and human samples in North Italy.
Goldman, "Structural features responsible for the biological stability of Histoplasma's virulence factor
CBP," Biochemistry, vol.
(3) Some species of GCS, chiefly SDSE, have many virulence factors
found in GAS like M protein, streptokinase, and streptolysins, but there are some that are missing like cysteine protease.