ache

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References in classic literature ?
Now, Mac, listen to me," Rose said very earnestly, though her voice shook a little and her heart ached.
1 : to suffer a dull continuous pain <My muscles ached from shoveling snow.
My heart ached for my mother, and today it aches for all those who suffer from disease and injury; but, no matter how deep my desire to ease that suffering may be, it cannot justify the destruction of a developing human life.