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Hehlmann, this is the first randomized, controlled trial to compare early treatment with alpha interferon a and allogeneic stem cell transplantation.
is a specialty bio-pharmaceutical company that is committed to the manufacturing and development of best-in-class allogeneic adult stem cells and stem cell factors for use by approved research institutions and hospitals for pre-clinical and clinical (human) trials.
ATIR(TM), a donor lymphocyte preparation depleted of alloreactive T-cells, is under development to reduce transplant related mortality (TRM) following an allogeneic hematopoietic stem cell transplantation (HSCT).
Figure 5: Indications for allogeneic hematopoietic stem cell transplantation worldwide in 2005, according to CIBMTR data 13
The EMA/CAT considers that Cellectis allogeneic engineered Chimeric Antigen Receptor (CAR+) T-cells fall within the definition of a Gene Therapy Medicinal Product.
People who receive allogeneic bone marrow or solid organ transplants are at high risk to CMV infection which can lead to severe conditions such as pneumonitis or hepatitis or complications such as acute or chronic rejection of the transplant.
today announced successful initial safety results following commencement of the world's first clinical trial to use allogeneic adult stem cells obtained from an unrelated, universal donor to treat patients with congestive heart failure.
Stemedica's bone marrow-derived, allogeneic itMSCs are unique because they are grown under hypoxic conditions that more closely resemble the environment in which they live in the body.
The candidates from UCART (for Universal Chimeric Antigen Receptor T cells) product family are allogeneic cell therapy products based on the CAR (Chimeric Antigen Receptor) technology combined with genome engineering.
The secondary objectives are to evaluate the activity of maribavir in preventing CMV reactivation in CMV seropositive recipients of allogeneic stem cell transplants, to evaluate the pharmacokinetics in the subject population, and to select a dose or doses of maribavir to be used in the Phase 8 trial.
We published evidence in 2004 showing that undifferentiated hESCs are immunoprivileged, which means they are minimally recognized by allogeneic human immune cells in vitro," said Thomas B.