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Both doses of alprostadil were associated with a significant vasodilatory response.
Presentation Title: Excitatory effects produced by topical application of a specially formulated alprostadil cream on the hypothelamic and amygdala neuronal activities.
Alprostadil is a well known vasodilator which can enhance local microcirculation by inducing capillary dilation and neovascularization.
NexMed is also developing Alprox-TD, its topical alprostadil treatment for male impotence.
Alprostadil is a hormone-like substance that is commonly found in the body, and has been used for years to treat male sexual dysfunction.
The podium presentation titled, "At-Home Use of Topical Alprostadil for the Treatment of Postmenopausal Women with Sexual Arousal Disorder (FSAD)," was presented by Marc Gittelman, M.
ALISTA(TM), a proprietary formulation of alprostadil, applied topically to the female genitalia, for the treatment of Female Sexual Arousal Disorder, was found in recent trials to improve the level of sexual satisfaction of postmenopausal women.
NexMed's Director of Exploratory Development, will deliver a podium presentation entitled, "Topical Application of Alprostadil Cream in Combination with a Local Anesthetic for the Treatment of Premature Ejaculation (PE).
Alprox-TD(R) is an easy to use topical cream that that is applied to the tip of the penis and incorporates alprostadil (PGE1) with the patented NexACT(R) transdermal delivery technology.
Femprox(TM) is NexMed's proprietary cream for the treatment of female sexual arousal disorder ("FSAD") and incorporates the active ingredient, alprostadil, with the patented NexACT(R) transdermal penetration enhancement technology.
Phase 2 trials suggest that SEPA will take alprostadil through the skin and into the penile arteries that engorge the penis with blood when a man is sexually stimulated.