alter

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alter

verb adapt, adjust, amend, change, commutare, commute, convert, deviate, innovate, invert, make innovations, metamorphose, moderate, modulate, mutare, qualify, rearrange, recast, reorganize, temper, transform, transmogrify, turn, variegate, vary
Associated concepts: alter a document, alter a will, forgery, fraud
See also: adapt, amend, change, commute, condition, convert, countervail, denature, edit, emend, falsify, fix, fluctuate, qualify, rectify, repair, revise, tamper, transform, vary

TO ALTER. To change. Alterations are made either in the contract itself, or in the instrument which is evidence of it. The contract may at any time be altered with the consent of the parties, and the alteration may be either in writing or not in writing.
     2. It is a general rule that the terms of a contract under seal, cannot be changed by a parol agreement. Cooke, 500; 3 Blackf. R. 353; 4 Bibb. 1. But it has been decided that an alteration of a contract by specialty, made by parol, makes it all parol. 2 Watts, 451; 1 Wash. R. 170; 4 Cowen, 564; 3 Harr. & John. 438; 9 Pick. 298; 1 East, R. 619; but see 3 S.& R. 579.
     3. When the contract is, in writing, but not under seal, it may be varied by parol, and the whole will make but one agreement. 9 Cowen, 115; 5.N. H. Rep. 99; 6 Harr. & John, 38; 18 John. 420; 1 John. Cas. 22; 5 Cowen, 606; Pet. C. C. R. 221; 1 Fairf. 414.
     4. When the contract is evidenced by a specialty, and it is altered by parol, the whole will be considered as a parol agreement. 2 Watt 451; 9 Pick. 298. For alteration of instruments see Erasure; Interlineation. See, generally, 7 Greenl. 76, 121, 394; 15 John. 200; 2 Penna. R. 454.

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Exposure to very low doses of endocrine disrupting chemicals (EDCs) during fetal life permanently alters brain development and behavior in animals and humans.
Realizing that something other than cholinesterase inhibition was affecting the fetus, a team from Duke University led by Theodore Slotkin gradually began to demonstrate that other mechanisms of action of CPF alter prenatal development of the brain and behavior and that the embryo and fetus are sensitive to cholinesterase inhibition at doses that would not be toxic to an adult (Qiao et al.
Other factors alter the color of hair samples, too, reports Wis-Surel.
More likely possibilities are that inappropriate exposure to estrogenic compounds alters the deposition of extracellular matrix molecules or signaling molecules such as the neurotrophins, which are crucial for the survival and differentiation of neural crest-derived structures (Chao and Hempstead 1995; Farinas 1999; Lewin and Barde 1996).
Scientists seek to understand ethylene because it helps plants alter their growth and development in response to the environment.
Concentrations of a common toxicant too low to cause reproductive abnormalities can still alter behavior in rats, according to a team of researchers led by Vincent Markowski of the University of Southern Maine in Portland [EHP 109:621-627].
Indeed, it may well be found that some of the symptoms of clinical syndromes not currently thought to be mediated by calcium channels may arise because defective intracellular signaling alters the function of genetically normal channel subunits.