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7) At that time, electron microscopy, microanalytical studies, experimental procedures, and an epidemiologic study demonstrated that the lesion is caused by the presence of an aluminum adjuvant used in vaccines against hepatitis A and B virus and tetanus toxoid; the aluminum remains accumulated at the site of injection.
an aluminum adjuvant, which is the only one approved by the (Food and Drug Administration) to be used in humans, and I mix that microemulsion with the aluminum compound, .
The technology utilizes precise lyophilization of protein immunogens with conventional aluminum adjuvants in combination with secondary adjuvants for rapid onset of protective immunity with the fewest number of vaccinations.