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In general, management of pneumomediastinum requires surgical correction of any mucosal disruption, treatment of any infectious causes, and elimination of contributors to increased alveolar pressure such as bronchospasm or positive-pressure ventilation (4).
Whereas flow and mouth pressure (Pmo) are easily measured at the mouth, alveolar pressure is derived from the mouth pressure-time transient Pmo(t) during a brief interruption of tidal breathing.
The volume of compressed gas will depend on alveolar pressure and absolute lung volume, which, in turn, depends on the interaction of respiratory muscle strength and force-velocity relationship, effort, hyperinflation and airway resistance [5].