The manifestations in diabetic limb angiopathy
diseases were commonly thickened endarterium lack or out of flatness and partial artherosclerotic plaques of different sizes protruding towards lumen which led to arterial-ste- nosis in different degrees or even block.
Although the angiographic findings were characteristic of vasculitis arising from an inflammatory process such as infection or as a result of medication, they were also consistent with the description of postpartum cerebral angiopathy
A deep hemispheric/brainstem pattern is suggestive of hypertensive vasculopathy while a strictly lobar pattern is suggestive of cerebral amyloid angiopathy
1) The pathophysiology of a dural AVF includes high-flow shunting that results in angiopathy
on both the venous and arterial sides, with segmental dilatation of blood vessels that may lead to hemorrhage and/or venous congestion.
Therefore, pharmacologic or biochemical interventions that reduce synthesis of lipid mediators of aggregation could prevent the development of diabetic angiopathy
A similar clinical picture can occur with repeated lobar hemorrhages; these are occasionally seen in hypertension but are more common in cerebral amyloid angiopathy
, a condition that is common in Alzheimer's disease.
Neurochem's research team has been working with international amyloid experts on the development of therapeutic cures to amyloid-related diseases, including Alzheimer's Disease, Secondary Amyloidosis, Diabetes Type II and Hemorrhagic Stroke due to Cerebral Amyloid Angiopathy
Cerebral amyloid angiopathy
causing large contralateral hemorrhage during surgery for lobar hemorrhage: A case report.
results from accelerated atherosclerosis, produces thickening of basement membrane.
It is also an aspect of cerebral amyloid angiopathy
(CAA), a condition associated with AD in which toxic beta-amyloid proteins build up in blood vessel walls.
Previous longitudinal studies of cerebral microbleeds were smaller and focused on patients seen at memory clinics or patients with cerebral amyloid angiopathy
instead of the general population.
The most frequent presentation of intracranial amyloid is as cerebral amyloid angiopathy
, or as deposits within the senile plaques of Alzheimer disease.